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The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a blood disease that disrupts normal function of the hematopoietic system. Despite the great progress made in terms of molecular therapies for CML, there remain large gaps in our understanding. By comparing mathematical models that describe CML progression and etiol...

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Detalhes bibliográficos
Main Authors: MacLean, Adam L., Filippi, Sarah, Stumpf, Michael P. H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956166/
https://ncbi.nlm.nih.gov/pubmed/24567385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317072111
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