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Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia

Haematopoietic stem cell dynamics regulate healthy blood cell production and are disrupted during leukaemia. Competition models of cellular species help to elucidate stem cell dynamics in the bone marrow microenvironment (or niche), and to determine how these dynamics impact leukaemia progression. H...

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Dades bibliogràfiques
Publicat a:J Theor Biol
Autors principals: Crowell, Helena L., MacLean, Adam L., Stumpf, Michael P.H.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880151/
https://ncbi.nlm.nih.gov/pubmed/27130539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2016.04.002
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