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Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia

Haematopoietic stem cell dynamics regulate healthy blood cell production and are disrupted during leukaemia. Competition models of cellular species help to elucidate stem cell dynamics in the bone marrow microenvironment (or niche), and to determine how these dynamics impact leukaemia progression. H...

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Detalhes bibliográficos
Publicado no:J Theor Biol
Main Authors: Crowell, Helena L., MacLean, Adam L., Stumpf, Michael P.H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880151/
https://ncbi.nlm.nih.gov/pubmed/27130539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2016.04.002
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