Single cell transcriptomics of human epidermis identifies basal stem cell transition states

How stem cells give rise to epidermis is unclear despite the crucial role the epidermis plays in barrier and appendage formation. Here we use single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular epidermis and find four spatially distinct stem cell populati...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Wang, Shuxiong, Drummond, Michael L., Guerrero-Juarez, Christian F., Tarapore, Eric, MacLean, Adam L., Stabell, Adam R., Wu, Stephanie C., Gutierrez, Guadalupe, That, Bao T., Benavente, Claudia A., Nie, Qing, Atwood, Scott X.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447770/
https://ncbi.nlm.nih.gov/pubmed/32843640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18075-7
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