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Single cell transcriptomics of human epidermis identifies basal stem cell transition states

How stem cells give rise to epidermis is unclear despite the crucial role the epidermis plays in barrier and appendage formation. Here we use single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular epidermis and find four spatially distinct stem cell populati...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Wang, Shuxiong, Drummond, Michael L., Guerrero-Juarez, Christian F., Tarapore, Eric, MacLean, Adam L., Stabell, Adam R., Wu, Stephanie C., Gutierrez, Guadalupe, That, Bao T., Benavente, Claudia A., Nie, Qing, Atwood, Scott X.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447770/
https://ncbi.nlm.nih.gov/pubmed/32843640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18075-7
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