The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

Por Brabletz, Simone, Brabletz, Thomas
Publicado em 2010

Road to perdition: Zeb1-dependent and –independent ways to metastasis

Por Brabletz, Simone, Brabletz, Thomas, Stemmler, Marc P.
Publicado no Cell Cycle (2017)

The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors

Por Mock, Kerstin, Preca, Bogdan-Tiberius, Brummer, Tilman, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Publicado no Oncotarget (2015)

The ZEB1/miR-200c feedback loop regulates invasion via actin interacting proteins MYLK and TKS5

Por Sundararajan, Vignesh, Gengenbacher, Nicolas, Stemmler, Marc P., Kleemann, Julia A., Brabletz, Thomas, Brabletz, Simone
Publicado no Oncotarget (2015)

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

Por Lehmann, Waltraut, Mossmann, Dirk, Kleemann, Julia, Mock, Kerstin, Meisinger, Chris, Brummer, Tilman, Herr, Ricarda, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Publicado no Nat Commun (2016)

The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells

Por Brabletz, Simone, Bajdak, Karolina, Meidhof, Simone, Burk, Ulrike, Niedermann, Gabriele, Firat, Elke, Wellner, Ulrich, Dimmler, Arno, Faller, Gerhard, Schubert, Jörg, Brabletz, Thomas
Publicado em 2011

MicroRNAs coordinately regulate protein complexes

Por Sass, Steffen, Dietmann, Sabine, Burk, Ulrike, Brabletz, Simone, Lutter, Dominik, Kowarsch, Andreas, Mayer, Klaus F, Brabletz, Thomas, Ruepp, Andreas, Theis, Fabian, Wang, Yu
Publicado em 2011

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

Por Preca, Bogdan-Tiberius, Bajdak, Karolina, Mock, Kerstin, Lehmann, Waltraut, Sundararajan, Vignesh, Bronsert, Peter, Matzge-Ogi, Alexandra, Orian-Rousseau, Véronique, Brabletz, Simone, Brabletz, Thomas, Maurer, Jochen, Stemmler, Marc P.
Publicado no Oncotarget (2017)

An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation

Por Haensel, Daniel, Sun, Peng, MacLean, Adam L, Ma, Xianghui, Zhou, Yuan, Stemmler, Marc P, Brabletz, Simone, Berx, Geert, Plikus, Maksim V, Nie, Qing, Brabletz, Thomas, Dai, Xing
Publicado no EMBO Rep (2018)

Genome‐wide cooperation of EMT transcription factor ZEB1 with YAP and AP‐1 in breast cancer

Por Feldker, Nora, Ferrazzi, Fulvia, Schuhwerk, Harald, Widholz, Sebastian A, Guenther, Kerstin, Frisch, Isabell, Jakob, Kathrin, Kleemann, Julia, Riegel, Dania, Bönisch, Ulrike, Lukassen, Sören, Eccles, Rebecca L, Schmidl, Christian, Stemmler, Marc P, Brabletz, Thomas, Brabletz, Simone
Publicado no EMBO J (2020)

Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure

Por Carpinelli, Marina R., de Vries, Michael E., Auden, Alana, Butt, Tariq, Deng, Zihao, Partridge, Darren D., Miles, Lee B., Georgy, Smitha R., Haigh, Jody J., Darido, Charbel, Brabletz, Simone, Brabletz, Thomas, Stemmler, Marc P., Dworkin, Sebastian, Jane, Stephen M.
Publicado no Dis Model Mech (2020)

ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat

Por Meidhof, Simone, Brabletz, Simone, Lehmann, Waltraut, Preca, Bogdan-Tiberius, Mock, Kerstin, Ruh, Manuel, Schüler, Julia, Berthold, Maria, Weber, Anika, Burk, Ulrike, Lübbert, Michael, Puhr, Martin, Culig, Zoran, Wellner, Ulrich, Keck, Tobias, Bronsert, Peter, Küsters, Simon, Hopt, Ulrich T, Stemmler, Marc P, Brabletz, Thomas
Publicado no EMBO Mol Med (2015)

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

Por Siebzehnrubl, Florian A, Silver, Daniel J, Tugertimur, Bugra, Deleyrolle, Loic P, Siebzehnrubl, Dorit, Sarkisian, Matthew R, Devers, Kelly G, Yachnis, Antony T, Kupper, Marius D, Neal, Daniel, Nabilsi, Nancy H, Kladde, Michael P, Suslov, Oleg, Brabletz, Simone, Brabletz, Thomas, Reynolds, Brent A, Steindler, Dennis A
Publicado em 2013