The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors

Tumor cell invasion, dissemination and metastasis is triggered by an aberrant activation of epithelial-to-mesenchymal transition (EMT), often mediated by the transcription factor ZEB1. Disseminating tumor cells must acquire specific features that allow them to colonize at different organ sites. Here...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mock, Kerstin, Preca, Bogdan-Tiberius, Brummer, Tilman, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546475/
https://ncbi.nlm.nih.gov/pubmed/25973542
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