ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

Early dissemination, metastasis and therapy resistance are central hallmarks of aggressive cancer types and the leading cause of cancer-associated deaths. The EMT-inducing transcriptional repressor ZEB1 is a crucial stimulator of these processes, particularly by coupling the activation of cellular m...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lehmann, Waltraut, Mossmann, Dirk, Kleemann, Julia, Mock, Kerstin, Meisinger, Chris, Brummer, Tilman, Herr, Ricarda, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756710/
https://ncbi.nlm.nih.gov/pubmed/26876920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10498
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