The ZEB1/miR-200c feedback loop regulates invasion via actin interacting proteins MYLK and TKS5

Epithelial to mesenchymal transition (EMT) is a developmental process which is aberrantly activated during cancer invasion and metastasis. Elevated expression of EMT-inducers like ZEB1 enables tumor cells to detach from the primary tumor and invade into the surrounding tissue. The main antagonist of...

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Udgivet i:Oncotarget
Main Authors: Sundararajan, Vignesh, Gengenbacher, Nicolas, Stemmler, Marc P., Kleemann, Julia A., Brabletz, Thomas, Brabletz, Simone
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694975/
https://ncbi.nlm.nih.gov/pubmed/26334100
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