The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells

Notch signalling is important for development and tissue homeostasis and activated in many human cancers. Nevertheless, mutations in Notch pathway components are rare in solid tumours. ZEB1 is an activator of an epithelial–mesenchymal transition (EMT) and has crucial roles in tumour progression towa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brabletz, Simone, Bajdak, Karolina, Meidhof, Simone, Burk, Ulrike, Niedermann, Gabriele, Firat, Elke, Wellner, Ulrich, Dimmler, Arno, Faller, Gerhard, Schubert, Jörg, Brabletz, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041948/
https://ncbi.nlm.nih.gov/pubmed/21224848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.349
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