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The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
Notch signalling is important for development and tissue homeostasis and activated in many human cancers. Nevertheless, mutations in Notch pathway components are rare in solid tumours. ZEB1 is an activator of an epithelial–mesenchymal transition (EMT) and has crucial roles in tumour progression towa...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041948/ https://ncbi.nlm.nih.gov/pubmed/21224848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.349 |
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