Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure

Cleft lip and palate are common birth defects resulting from failure of the facial processes to fuse during development. The mammalian grainyhead-like (Grhl1-3) genes play key roles in a number of tissue fusion processes including neurulation, epidermal wound healing and eyelid fusion. One family me...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Carpinelli, Marina R., de Vries, Michael E., Auden, Alana, Butt, Tariq, Deng, Zihao, Partridge, Darren D., Miles, Lee B., Georgy, Smitha R., Haigh, Jody J., Darido, Charbel, Brabletz, Simone, Brabletz, Thomas, Stemmler, Marc P., Dworkin, Sebastian, Jane, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104862/
https://ncbi.nlm.nih.gov/pubmed/32005677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.042218
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