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Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma
BACKGROUND: The developmental transcription factor Grainyhead-like 3 (GRHL3) plays a critical tumor suppressor role in the mammalian epidermis through direct regulation of PTEN and the PI3K/AKT/mTOR signaling pathway. GRHL3 is highly expressed in all tissues derived from the surface ectoderm, includ...
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| Publicado no: | J Natl Cancer Inst |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836819/ https://ncbi.nlm.nih.gov/pubmed/26063791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv152 |
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