Exploring intermediate cell states through the lens of single cells

le MacLean, Adam L., Hong, Tian, Nie, Qing
Foilsithe in Curr Opin Syst Biol (2018)

The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia

le MacLean, Adam L., Filippi, Sarah, Stumpf, Michael P. H.
Foilsithe 2014

Cell lineage and communication network inference via optimization for single-cell transcriptomics

le Wang, Shuxiong, Karikomi, Matthew, MacLean, Adam L, Nie, Qing
Foilsithe in Nucleic Acids Res (2019)

scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data

le Jin, Suoqin, MacLean, Adam L, Peng, Tao, Nie, Qing
Foilsithe in Bioinformatics (2018)

Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled

le MacLean, Adam L., Lo Celso, Cristina, Stumpf, Michael P. H.
Foilsithe 2013

Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia

le Crowell, Helena L., MacLean, Adam L., Stumpf, Michael P.H.
Foilsithe in J Theor Biol (2016)

Parameter-free methods distinguish Wnt pathway models and guide design of experiments

le MacLean, Adam L., Rosen, Zvi, Byrne, Helen M., Harrington, Heather A.
Foilsithe in Proc Natl Acad Sci U S A (2015)

Cellular population dynamics control the robustness of the stem cell niche

le MacLean, Adam L., Kirk, Paul D. W., Stumpf, Michael P. H.
Foilsithe in Biol Open (2015)

Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model

le MacLean, Adam L., Harrington, Heather A., Stumpf, Michael P. H., Hansen, Marc D. H.
Foilsithe in Biomedicines (2014)

A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions

le Peng, Tao, Liu, Linan, MacLean, Adam L, Wong, Chi Wut, Zhao, Weian, Nie, Qing
Foilsithe in BMC Syst Biol (2017)

Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch

le Sharma, Praveer P., MacLean, Adam L., Meinecke, Lina, Clouthier, David E., Nie, Qing, Schilling, Thomas F.
Foilsithe in Genesis (2018)

Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis

le Lambert, Ben, MacLean, Adam L., Fletcher, Alexander G., Combes, Alexander N., Little, Melissa H., Byrne, Helen M.
Foilsithe in J Math Biol (2018)

An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation

le Haensel, Daniel, Sun, Peng, MacLean, Adam L, Ma, Xianghui, Zhou, Yuan, Stemmler, Marc P, Brabletz, Simone, Berx, Geert, Plikus, Maksim V, Nie, Qing, Brabletz, Thomas, Dai, Xing
Foilsithe in EMBO Rep (2018)

Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points

le Vainieri, Maria L., Blagborough, Andrew M., MacLean, Adam L., Haltalli, Myriam L. R., Ruivo, Nicola, Fletcher, Helen A., Stumpf, Michael P. H., Sinden, Robert E., Lo Celso, Cristina
Foilsithe in Open Biol (2016)

Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics

le Haensel, Daniel, Jin, Suoqin, Sun, Peng, Cinco, Rachel, Dragan, Morgan, Nguyen, Quy, Cang, Zixuan, Gong, Yanwen, Vu, Remy, MacLean, Adam L., Kessenbrock, Kai, Gratton, Enrico, Nie, Qing, Dai, Xing
Foilsithe in Cell Rep (2020)

Single cell transcriptomics of human epidermis identifies basal stem cell transition states

le Wang, Shuxiong, Drummond, Michael L., Guerrero-Juarez, Christian F., Tarapore, Eric, MacLean, Adam L., Stabell, Adam R., Wu, Stephanie C., Gutierrez, Guadalupe, That, Bao T., Benavente, Claudia A., Nie, Qing, Atwood, Scott X.
Foilsithe in Nat Commun (2020)

Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure

le Rando, Halie M., MacLean, Adam L., Lee, Alexandra J., Lordan, Ronan, Ray, Sandipan, Bansal, Vikas, Skelly, Ashwin N., Sell, Elizabeth, Dziak, John J., Shinholster, Lamonica, McGowan, Lucy D’Agostino, Guebila, Marouen Ben, Wellhausen, Nils, Knyazev, Sergey, Boca, Simina M., Capone, Stephen, Qi, Yanjun, Park, YoSon, Sun, Yuchen, Mai, David, Boerckel, Joel D, Brueffer, Christian, Byrd, James Brian, Kamil, Jeremy P., Wang, Jinhui, Velazquez, Ryan, Szeto, Gregory L, Barton, John P., Goel, Rishi Raj, Mangul, Serghei, Lubiana, Tiago, Gitter, Anthony, Greene, Casey S.
Foilsithe in ArXiv (2021)