Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

מאת Masui, Toshihiko, Long, Qiaoming, Beres, Thomas M., Magnuson, Mark A., MacDonald, Raymond J.
יצא לאור 2007

Experimental control of pancreatic development and maintenance

מאת Holland, Andrew M., Hale, Michael A., Kagami, Hideaki, Hammer, Robert E., MacDonald, Raymond J.
יצא לאור 2002

Multiple Transcriptional Mechanisms Control Ptf1a Levels during Neural Development Including Autoregulation by the PTF1-J Complex

מאת Meredith, David M., Masui, Toshihiko, Swift, Galvin H., MacDonald, Raymond J., Johnson, Jane E.
יצא לאור 2009

PTF1 Is an Organ-Specific and Notch-Independent Basic Helix-Loop-Helix Complex Containing the Mammalian Suppressor of Hairless (RBP-J) or Its Paralogue, RBP-L

מאת Beres, Thomas M., Masui, Toshihiko, Swift, Galvin H., Shi, Ling, Henke, R. Michael, MacDonald, Raymond J.
יצא לאור 2006

Transcriptional Autoregulation Controls Pancreatic Ptf1a Expression during Development and Adulthood

מאת Masui, Toshihiko, Swift, Galvin H., Hale, Michael A., Meredith, David M., Johnson, Jane E., MacDonald, Raymond J.
יצא לאור 2008

Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10

מאת Kobberup, Sune, Schmerr, Martin, Dang, My-Linh, Nyeng, Pia, Jensen, Jan N., MacDonald, Raymond J., Jensen, Jan
יצא לאור 2009

Dominant and context-specific control of endodermal organ allocation by Ptf1a

מאת Willet, Spencer G., Hale, Michael A., Grapin-Botton, Anne, Magnuson, Mark A., MacDonald, Raymond J., Wright, Christopher V. E.
הוצא לאור ב Development (2014)

Conditional Expression of Smad7 in Pancreatic β Cells Disrupts TGF-β Signaling and Induces Reversible Diabetes Mellitus

מאת Smart, Nora G, Apelqvist, Åsa A, Gu, Xueying, Harmon, Erin B, Topper, James N, MacDonald, Raymond J, Kim, Seung K
יצא לאור 2006

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function

מאת Holmstrom, Sam R., Deering, Tye, Swift, Galvin H., Poelwijk, Frank J., Mangelsdorf, David J., Kliewer, Steven A., MacDonald, Raymond J.
יצא לאור 2011

Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells

מאת Afelik, Solomon, Qu, Xiaoling, Hasrouni, Edy, Bukys, Michael A., Deering, Tye, Nieuwoudt, Stephan, Rogers, William, MacDonald, Raymond J., Jensen, Jan
יצא לאור 2012

Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord

מאת Henke, R. Michael, Savage, Trisha K., Meredith, David M., Glasgow, Stacey M., Hori, Kei, Dumas, Judy, MacDonald, Raymond J., Johnson, Jane E.
יצא לאור 2009

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

מאת Masui, Toshihiko, Swift, Galvin H., Deering, Tye, Shen, Chengcheng, Coats, Ward S., Long, Qiaoming, Elsässer, Hans-Peter, Magnuson, Mark A., MacDonald, Raymond J.
יצא לאור 2010

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

מאת Hale, Michael A., Swift, Galvin H., Hoang, Chinh Q., Deering, Tye G., Masui, Toshi, Lee, Youn-Kyoung, Xue, Jumin, MacDonald, Raymond J.
יצא לאור 2014

Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism

מאת Krah, Nathan M., Narayanan, Shuba M., Yugawa, Deanne E., Straley, Julie A., Wright, Christopher V. E., MacDonald, Raymond J., Murtaugh, L. Charles
הוצא לאור ב Dev Cell (2019)

An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2)

מאת Swift, Galvin H., Liu, Ying, Rose, Scott D., Bischof, Larry J., Steelman, Scott, Buchberg, Arthur M., Wright, Christopher V. E., MacDonald, Raymond J.
יצא לאור 1998

Pdx1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression

מאת Gauthier, Benoit R., Wiederkehr, Andreas, Baquié, Maturin, Dai, Chunhua, Powers, Alvin C., Kerr-Conte, Julie, Pattou, François, MacDonald, Raymond J., Ferrer, Jorge, Wollheim, Claes B.
יצא לאור 2009

MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice

מאת Jiang, Mei, Azevedo-Pouly, Ana C., Deering, Tye G., Hoang, Chinh Q., DiRenzo, Daniel, Hess, David A., Konieczny, Stephen F., Swift, Galvin H., MacDonald, Raymond J.
הוצא לאור ב Mol Cell Biol (2016)

Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism

מאת Ahnfelt-Rønne, Jonas, Jørgensen, Mette C., Klinck, Rasmus, Jensen, Jan N., Füchtbauer, Ernst-Martin, Deering, Tye, MacDonald, Raymond J., Wright, Chris V. E., Madsen, Ole D., Serup, Palle
יצא לאור 2012

MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response

מאת Hess, David A., Strelau, Katherine M., Karki, Anju, Jiang, Mei, Azevedo-Pouly, Ana C., Lee, Ann-Hwee, Deering, Tye G., Hoang, Chinh Q., MacDonald, Raymond J., Konieczny, Stephen F.
הוצא לאור ב Mol Cell Biol (2016)

Isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation

מאת Houghton, Jayne A.L., Swift, Galvin H., Shaw-Smith, Charles, Flanagan, Sarah E., de Franco, Elisa, Caswell, Richard, Hussain, Khalid, Mohamed, Sarar, Abdulrasoul, Majedah, Hattersley, Andrew T., MacDonald, Raymond J., Ellard, Sian
הוצא לאור ב Diabetes (2016)