Dominant and context-specific control of endodermal organ allocation by Ptf1a

The timing and gene regulatory logic of organ-fate commitment from within the posterior foregut of the mammalian endoderm is largely unexplored. Transient misexpression of a presumed pancreatic-commitment transcription factor, Ptf1a, in embryonic mouse endoderm (Ptf1a(EDD)) dramatically expanded the...

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Bibliografische gegevens
Gepubliceerd in:Development
Hoofdauteurs: Willet, Spencer G., Hale, Michael A., Grapin-Botton, Anne, Magnuson, Mark A., MacDonald, Raymond J., Wright, Christopher V. E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302917/
https://ncbi.nlm.nih.gov/pubmed/25371369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.114165
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