Dominant and context-specific control of endodermal organ allocation by Ptf1a

The timing and gene regulatory logic of organ-fate commitment from within the posterior foregut of the mammalian endoderm is largely unexplored. Transient misexpression of a presumed pancreatic-commitment transcription factor, Ptf1a, in embryonic mouse endoderm (Ptf1a(EDD)) dramatically expanded the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Willet, Spencer G., Hale, Michael A., Grapin-Botton, Anne, Magnuson, Mark A., MacDonald, Raymond J., Wright, Christopher V. E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302917/
https://ncbi.nlm.nih.gov/pubmed/25371369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.114165
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