The Context-Dependence of Mutations: A Linkage of Formalisms

af Poelwijk, Frank J., Krishna, Vinod, Ranganathan, Rama
Udgivet i PLoS Comput Biol (2016)

Learning the pattern of epistasis linking genotype and phenotype in a protein

af Poelwijk, Frank J., Socolich, Michael, Ranganathan, Rama
Udgivet i Nat Commun (2019)

Evolutionary Potential of a Duplicated Repressor-Operator Pair: Simulating Pathways Using Mutation Data

af Poelwijk, Frank J, Kiviet, Daniel J, Tans, Sander J
Udgivet 2006

The spatial architecture of protein function and adaptation

af McLaughlin, Richard N., Poelwijk, Frank J., Raman, Arjun, Gosal, Walraj S., Ranganathan, Rama
Udgivet 2012

Optimality and evolution of transcriptionally regulated gene expression

af Poelwijk, Frank J, Heyning, Philip D, de Vos, Marjon GJ, Kiviet, Daniel J, Tans, Sander J
Udgivet 2011

Environmental Dependence of Genetic Constraint

af de Vos, Marjon G. J., Poelwijk, Frank J., Battich, Nico, Ndika, Joseph D. T., Tans, Sander J.
Udgivet 2013

Mutation effects predicted from sequence co-variation

af Hopf, Thomas A., Ingraham, John B., Poelwijk, Frank J., Schärfe, Charlotta P.I., Springer, Michael, Sander, Chris, Marks, Debora S.
Udgivet i Nat Biotechnol (2017)

Inferring protein 3D structure from deep mutation scans

af Rollins, Nathan J., Brock, Kelly P., Poelwijk, Frank J., Stiffler, Michael A., Gauthier, Nicholas P., Sander, Chris, Marks, Debora S.
Udgivet i Nat Genet (2019)

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function

af Holmstrom, Sam R., Deering, Tye, Swift, Galvin H., Poelwijk, Frank J., Mangelsdorf, David J., Kliewer, Steven A., MacDonald, Raymond J.
Udgivet 2011