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Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10

Fgf10 is a critical component of mesenchymal-to-epithelial signaling during endodermal development. In the Fgf10 null pancreas, the embryonic progenitor population fails to expand, while ectopic Fgf10 expression forces progenitor arrest and organ hyperplasia. Using a conditional Fgf10 gain-of-functi...

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Autores principales: Kobberup, Sune, Schmerr, Martin, Dang, My-Linh, Nyeng, Pia, Jensen, Jan N., MacDonald, Raymond J., Jensen, Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849919/
https://ncbi.nlm.nih.gov/pubmed/19969077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.11.005
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