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Endocrine-exocrine signaling drives obesity-associated pancreatic ductal adenocarcinoma
Obesity is a major modifiable risk factor for pancreatic ductal adenocarcinoma (PDAC), yet how and when obesity contributes to PDAC progression is not well understood. Leveraging an autochthonous mouse model, we demonstrate a causal and reversible role for obesity in early PDAC progression, showing...
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| izdano v: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7266008/ https://ncbi.nlm.nih.gov/pubmed/32304665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.03.062 |
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