Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats

著者: Perry, Rachel J., Rabin-Court, Aviva, Song, Joongyu D., Cardone, Rebecca L., Wang, Yongliang, Kibbey, Richard G., Shulman, Gerald I.
出版年 Nat Commun (2019)

Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms

著者: Ferrandino, Giuseppe, Kaspari, Rachel R., Spadaro, Olga, Reyna-Neyra, Andrea, Perry, Rachel J., Cardone, Rebecca, Kibbey, Richard G., Shulman, Gerald I., Dixit, Vishwa Deep, Carrasco, Nancy
出版年 Proc Natl Acad Sci U S A (2017)

Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis

著者: Davis, Jeffrey C., Alves, Tiago C., Helman, Aharon, Chen, Jonathan C., Kenty, Jennifer H., Cardone, Rebecca L., Liu, David R., Kibbey, Richard G., Melton, Douglas A.
出版年 Cell Rep (2020)

Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents

著者: Perry, Rachel J., Cardone, Rebecca L., Petersen, Max C., Zhang, Dongyan, Fouqueray, Pascale, Hallakou-Bozec, Sophie, Bolze, Sébastien, Shulman, Gerald I., Petersen, Kitt Falk, Kibbey, Richard G.
出版年 Am J Physiol Endocrinol Metab (2016)

Acetate mediates a microbiome-brain-β cell axis promoting metabolic syndrome

著者: Perry, Rachel J., Peng, Liang, Barry, Natasha A., Cline, Gary W., Zhang, Dongyan, Cardone, Rebecca L., Petersen, Kitt Falk, Kibbey, Richard G., Goodman, Andrew L., Shulman, Gerald I.
出版年 Nature (2016)

N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis

著者: Grevengoed, Trisha J., Trammell, Samuel A. J., McKinney, Michele K., Petersen, Natalia, Cardone, Rebecca L., Svenningsen, Jens S., Ogasawara, Daisuke, Nexøe-Larsen, Christina C., Knop, Filip K., Schwartz, Thue W., Kibbey, Richard G., Cravatt, Benjamin F., Gillum, Matthew P.
出版年 Proc Natl Acad Sci U S A (2019)

Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health

著者: Abulizi, Abudukadier, Cardone, Rebecca L., Stark, Romana, Lewandowski, Sophie L., Zhao, Xiaojian, Hillion, Joelle, Ma, Lingjun, Sehgal, Raghav, Alves, Tiago C., Thomas, Craig, Kung, Charles, Wang, Bei, Siebel, Stephan, Andrews, Zane B., Mason, Graeme F., Rinehart, Jesse, Merrins, Matthew J., Kibbey, Richard G.
出版年 Cell Metab (2020)

Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production

著者: Gassaway, Brandon M., Cardone, Rebecca L., Padyana, Anil K., Petersen, Max C., Judd, Evan T., Hayes, Sebastian, Tong, Shuilong, Barber, Karl W., Apostolidi, Maria, Abulizi, Abudukadier, Sheetz, Joshua B., Kshitiz, Aerni, Hans R., Gross, Stefan, Kung, Charles, Samuel, Varman T., Shulman, Gerald I., Kibbey, Richard G., Rinehart, Jesse
出版年 Cell Rep (2019)

Mitochondrial GTP Links Nutrient Sensing to β Cell Health, Mitochondrial Morphology, and Insulin Secretion Independent of OxPhos

著者: Jesinkey, Sean R., Madiraju, Anila K., Alves, Tiago C., Yarborough, OrLando H., Cardone, Rebecca L., Zhao, Xiaojian, Parsaei, Yassmin, Nasiri, Ali R., Butrico, Gina, Liu, Xinran, Molina, Anthony J., Rountree, Austin M., Neal, Adam S., Wolf, Dane M., Sterpka, John, Philbrick, William M., Sweet, Ian R., Shirihai, Orian H., Kibbey, Richard G.
出版年 Cell Rep (2019)

Pyruvate kinase controls signal strength in the insulin secretory pathway

著者: Lewandowski, Sophie L., Cardone, Rebecca L., Foster, Hannah R., Ho, Thuong, Potapenko, Evgeniy, Poudel, Chetan, VanDeusen, Halena R., Sdao, Sophia M., Alves, Tiago C., Zhao, Xiaojian, Capozzi, Megan E., de Souza, Arnaldo H., Jahan, Ishrat, Thomas, Craig J., Nunemaker, Craig S., Davis, Dawn Belt, Campbell, Jonathan E., Kibbey, Richard G., Merrins, Matthew J.
出版年 Cell Metab (2020)

CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation

著者: Esteghamat, Fatemehsadat, Broughton, James S., Smith, Emily, Cardone, Rebecca, Tyagi, Tarun, Guerra, Mateus, Szabó, András, Ugwu, Nelson, Mani, Mitra V., Azari, Bani, Kayingo, Gerald, Chung, Sunny, Fathzadeh, Mohsen, Weiss, Ephraim, Bender, Jeffrey, Mane, Shrikant, Lifton, Richard P., Adeniran, Adebowale, Nathanson, Michael H., Gorelick, Fred S., Hwa, John, Sahin-Tóth, Miklós, Belfort-DeAguiar, Renata, Kibbey, Richard G., Mani, Arya
出版年 Nat Genet (2019)

Endocrine-exocrine signaling drives obesity-associated pancreatic ductal adenocarcinoma

著者: Chung, Katherine Minjee, Singh, Jaffarguriqbal, Lawres, Lauren, Dorans, Kimberly Judith, Garcia, Cathy, Burkhardt, Daniel B., Robbins, Rebecca, Bhutkar, Arjun, Cardone, Rebecca, Zhao, Xiaojian, Babic, Ana, Vayrynen, Sara A., Costa, Andressa Dias, Nowak, Jonathan A., Chang, Daniel T., Dunne, Richard F., Hezel, Aram F., Koong, Albert C., Wilhelm, Joshua J., Bellin, Melena D., Nylander, Vibe, Gloyn, Anna L., McCarthy, Mark I., Kibbey, Richard G., Krishnaswamy, Smita, Wolpin, Brian M., Jacks, Tyler, Fuchs, Charles S., Muzumdar, Mandar Deepak
出版年 Cell (2020)