Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms

Hypothyroidism, a metabolic disease characterized by low thyroid hormone (TH) and high thyroid-stimulating hormone (TSH) levels in the serum, is strongly associated with nonalcoholic fatty liver disease (NAFLD). Hypothyroidism-induced NAFLD has generally been attributed to reduced TH signaling in th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ferrandino, Giuseppe, Kaspari, Rachel R., Spadaro, Olga, Reyna-Neyra, Andrea, Perry, Rachel J., Cardone, Rebecca, Kibbey, Richard G., Shulman, Gerald I., Dixit, Vishwa Deep, Carrasco, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664516/
https://ncbi.nlm.nih.gov/pubmed/29073114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707797114
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