Insulin-Like Growth Factor Type 1 Receptor and Insulin Receptor Isoform Expression and Signaling in Mammary Epithelial Cells

di Rowzee, Anne M., Ludwig, Dale L., Wood, Teresa L.
Pubblicazione 2009

Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

di Ulanet, Danielle B., Ludwig, Dale L., Kahn, C. Ronald, Hanahan, Douglas
Pubblicazione 2010

225Ac‐labeled CD33‐targeting antibody reverses resistance to Bcl‐2 inhibitor venetoclax in acute myeloid leukemia models

di Garg, Ravendra, Allen, Kevin J. H., Dawicki, Wojciech, Geoghegan, Eileen M., Ludwig, Dale L., Dadachova, Ekaterina
Pubblicato in Cancer Med (2020)

Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy

di Dawicki, Wojciech, Allen, Kevin J.H., Garg, Ravendra, Geoghegan, Eileen M., Berger, Mark S., Ludwig, Dale L., Dadachova, Ekaterina
Pubblicato in Oncotarget (2020)

Daratumumab-(225)Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors

di Dawicki, Wojciech, Allen, Kevin J.H., Jiao, Rubin, Malo, Mackenzie E., Helal, Muath, Berger, Mark S., Ludwig, Dale L., Dadachova, Ekaterina
Pubblicato in Oncoimmunology (2019)

Transforming growth factor-β-stimulated clone-22 (TSC-22) is an androgen regulated gene that enhances apoptosis in prostate cancer following IGF-IR inhibition

di Sprenger, Cynthia C. T., Haugk, Kathleen, Sun, Shihua, Coleman, Ilsa, Nelson, Peter S., Vessella, Robert L., Ludwig, Dale L., Wu, Jennifer D., Plymate, Stephen R.
Pubblicazione 2009

Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes

di Kang, Yun (Kenneth), Hamzik, James, Felo, Michael, Qi, Bo, Lee, Julia, Ng, Stanley, Liebisch, Gregory, Shanehsaz, Behnam, Singh, Nripen, Persaud, Kris, Ludwig, Dale L, Balderes, Paul
Pubblicazione 2013

Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody

di Yin, Yongjun, Ren, Xiaodi, Smith, Craig, Guo, Qianxu, Malabunga, Maria, Guernah, Ilhem, Zhang, Yiwei, Shen, Juqun, Sun, Haijun, Chehab, Nabil, Loizos, Nick, Ludwig, Dale L., Ornitz, David M.
Pubblicato in Dis Model Mech (2016)

Dual Inhibition of Epidermal Growth Factor Receptor and Insulin-like Growth Factor Receptor I Reduces Angiogenesis and Tumor Growth in Cutaneous Squamous Cell Carcinoma

di Galer, Chad E., Corey, Christina L., Wang, Zhuoying, Younes, Maher N., Gomez-Rivera, Fernando, Jasser, Samar A., Ludwig, Dale L., El-Naggar, Adel K., Weber, Randal S., Myers, Jeffrey N.
Pubblicazione 2011

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

di O’Reilly, Kathryn E., Rojo, Fredi, She, Qing-Bai, Solit, David, Mills, Gordon B., Smith, Debra, Lane, Heidi, Hofmann, Francesco, Hicklin, Daniel J., Ludwig, Dale L., Baselga, Jose, Rosen, Neal
Pubblicazione 2006

Removal of a C-terminal serine residue proximal to the inter-chain disulfide bond of a human IgG1 lambda light chain mediates enhanced antibody stability and antibody dependent cel...

di Shen, Yang, Zeng, Lin, Zhu, Aiping, Blanc, Tim, Patel, Dipa, Pennello, Anthony, Bari, Amtul, Ng, Stanley, Persaud, Kris, Kang, Yun (Kenneth), Balderes, Paul, Surguladze, David, Hindi, Sagit, Zhou, Qinwei, Ludwig, Dale L., Snavely, Marshall
Pubblicazione 2013

Intrinsic Resistance to Cixutumumab is Conferred by Distinct Isoforms of the Insulin Receptor

di Forest, Amelie, Amatulli, Michael, Ludwig, Dale L., Damoci, Christopher B., Wang, Ying, Burns, Colleen A., Donoho, Gregory P., Zanella, Nina, Fiebig, Heinz H., Prewett, Marie C., Surguladze, David, DeLigio, James T., Houghton, Peter J., Smith, Malcolm A., Novosiadly, Ruslan
Pubblicato in Mol Cancer Res (2015)

An Open-label, Dose-Escalation Phase 1 Study of anti-TYRP1 monoclonal antibody IMC-20D7S for patients with relapsed or refractory melanoma

di Khalil, Danny N., Postow, Michael A., Ibrahim, Nageatte, Ludwig, Dale L., Cosaert, Jan, Kambhampati, Siva Rama Prasad, Tang, Shande, Grebennik, Dmitri, Kauh, John Sae Wook, Lenz, Heinz-Josef, Flaherty, Keith T., Hodi, F. Stephen, Lawrence, Donald P., Wolchok, Jedd D.
Pubblicato in Clin Cancer Res (2016)

Development of a Fully Human Anti-PDGFRβ Antibody That Suppresses Growth of Human Tumor Xenografts and Enhances Antitumor Activity of an Anti-VEGFR2 Antibody

di Shen, Juqun, Vil, Marie Danielle, Prewett, Marie, Damoci, Chris, Zhang, Haifan, Li, Huiling, Jimenez, Xenia, Deevi, Dhanvanthri S, Iacolina, Michelle, Kayas, Anthony, Bassi, Rajiv, Persaud, Kris, Rohoza-Asandi, Anna, Balderes, Paul, Loizos, Nick, Ludwig, Dale L, Tonra, James, Witte, Larry, Zhu, Zhenping
Pubblicazione 2009

Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054

di Li, Yiwen, Carpenito, Carmine, Wang, George, Surguladze, David, Forest, Amelie, Malabunga, Maria, Murphy, Mary, Zhang, Yiwei, Sonyi, Andreas, Chin, Darin, Burtrum, Douglas, Inigo, Ivan, Pennello, Anthony, Shen, Leyi, Malherbe, Laurent, Chen, Xinlei, Hall, Gerald, Haidar, Jaafar N., Ludwig, Dale L., Novosiadly, Ruslan D., Kalos, Michael
Pubblicato in J Immunother Cancer (2018)

Correction to: Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054

di Li, Yiwen, Carpenito, Carmine, Wang, George, Surguladze, David, Forest, Amelie, Malabunga, Maria, Murphy, Mary, Zhang, Yiwei, Sonyi, Andreas, Chin, Darin, Burtrum, Douglas, Inigo, Ivan, Pennello, Anthony, Shen, Leyi, Malherbe, Laurent, Chen, Xinlei, Hall, Gerald, Haidar, Jaafar N., Ludwig, Dale L., Novosiadly, Ruslan D., Kalos, Michael
Pubblicato in J Immunother Cancer (2018)

A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation

di Shen, Yang, Zeng, Lin, Novosyadlyy, Ruslan, Forest, Amelie, Zhu, Aiping, Korytko, Andrew, Zhang, Haifan, Eastman, Scott W, Topper, Michael, Hindi, Sagit, Covino, Nicole, Persaud, Kris, Kang, Yun, Burtrum, Douglas, Surguladze, David, Prewett, Marie, Chintharlapalli, Sudhakar, Wroblewski, Victor J, Shen, Juqun, Balderes, Paul, Zhu, Zhenping, Snavely, Marshall, Ludwig, Dale L
Pubblicato in MAbs (2015)