Intrinsic Resistance to Cixutumumab is Conferred by Distinct Isoforms of the Insulin Receptor

Despite a recent shift away from anti-insulin-like growth factor I receptor (IGF-IR) therapy, this target has been identified as a key player in the resistance mechanisms to various conventional and targeted agents, emphasizing its value as a therapy, provided that it is used in the right patient po...

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Bibliografiska uppgifter
I publikationen:Mol Cancer Res
Huvudupphovsmän: Forest, Amelie, Amatulli, Michael, Ludwig, Dale L., Damoci, Christopher B., Wang, Ying, Burns, Colleen A., Donoho, Gregory P., Zanella, Nina, Fiebig, Heinz H., Prewett, Marie C., Surguladze, David, DeLigio, James T., Houghton, Peter J., Smith, Malcolm A., Novosiadly, Ruslan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685019/
https://ncbi.nlm.nih.gov/pubmed/26263910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0279
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