Intrinsic Resistance to Cixutumumab is Conferred by Distinct Isoforms of the Insulin Receptor

Despite a recent shift away from anti-insulin-like growth factor I receptor (IGF-IR) therapy, this target has been identified as a key player in the resistance mechanisms to various conventional and targeted agents, emphasizing its value as a therapy, provided that it is used in the right patient po...

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Publicado en:Mol Cancer Res
Main Authors: Forest, Amelie, Amatulli, Michael, Ludwig, Dale L., Damoci, Christopher B., Wang, Ying, Burns, Colleen A., Donoho, Gregory P., Zanella, Nina, Fiebig, Heinz H., Prewett, Marie C., Surguladze, David, DeLigio, James T., Houghton, Peter J., Smith, Malcolm A., Novosiadly, Ruslan
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685019/
https://ncbi.nlm.nih.gov/pubmed/26263910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0279
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