Intrinsic Resistance to Cixutumumab is Conferred by Distinct Isoforms of the Insulin Receptor

Despite a recent shift away from anti-insulin-like growth factor I receptor (IGF-IR) therapy, this target has been identified as a key player in the resistance mechanisms to various conventional and targeted agents, emphasizing its value as a therapy, provided that it is used in the right patient po...

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Bibliografiset tiedot
Julkaisussa:Mol Cancer Res
Päätekijät: Forest, Amelie, Amatulli, Michael, Ludwig, Dale L., Damoci, Christopher B., Wang, Ying, Burns, Colleen A., Donoho, Gregory P., Zanella, Nina, Fiebig, Heinz H., Prewett, Marie C., Surguladze, David, DeLigio, James T., Houghton, Peter J., Smith, Malcolm A., Novosiadly, Ruslan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685019/
https://ncbi.nlm.nih.gov/pubmed/26263910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0279
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