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High-content molecular profiling of T-cell therapy in oncology

Recent clinical data have revealed the remarkable potential for T-cell-modulating agents to induce potent and durable responses in a subset of cancer patients. In this review, we discuss molecular approaches, platforms, and strategies that enable a broader interrogation of the activity of agents tha...

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Pubblicato in:Mol Ther Oncolytics
Autori principali: Novosiadly, Ruslan, Kalos, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008264/
https://ncbi.nlm.nih.gov/pubmed/27626060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.9
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