Pathogenesis and treatment of acquired idiopathic thrombotic thrombocytopenic purpura

Por Peyvandi, Flora, Palla, Roberta, Lotta, Luca A.
Publicado em 2010

Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease

Por Mannucci, Pier Mannuccio, Lotta, Luca A, Peyvandi, Flora
Publicado em 2010

Prevalence of Disease and Relationships between Laboratory Phenotype and Bleeding Severity in Platelet Primary Secretion Defects

Por Lotta, Luca A., Maino, Alberto, Tuana, Giacomo, Rossio, Raffaella, Lecchi, Anna, Artoni, Andrea, Peyvandi, Flora
Publicado em 2013

A novel CD46 mutation in a patient with microangiopathy clinically resembling thrombotic thrombocytopenic purpura and normal ADAMTS13 activity

Por Rossio, Raffaella, Lotta, Luca Andrea, Pontiggia, Silvia, Borsa, Nicolò Ghiringhelli, Garagiola, Isabella, Ardissino, Gianluigi, Mikovic, Danijela, Cugno, Massimo, Peyvandi, Flora
Publicado no Haematologica (2015)

Pregnancy complications in acquired thrombotic thrombocytopenic purpura: a case–control study

Por Ferrari, Barbara, Maino, Alberto, Lotta, Luca A, Artoni, Andrea, Pontiggia, Silvia, Trisolini, Silvia M, Malato, Alessandra, Rosendaal, Frits R, Peyvandi, Flora
Publicado no Orphanet J Rare Dis (2014)

Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis

Por Gorski, Marcin M., Lotta, Luca A., Pappalardo, Emanuela, de Haan, Hugoline G., Passamonti, Serena M., van Hylckama Vlieg, Astrid, Martinelli, Ida, Peyvandi, Flora
Publicado no PLoS One (2016)

Definitions of metabolic health and risk of future type 2 diabetes in body mass index categories: a systematic review and network meta-analysis

Por Lotta, Luca A., Abbasi, Ali, Sharp, Stephen J., Sahlqvist, Anna-Stina, Waterworth, Dawn, Brosnan, Julia M., Scott, Robert A., Langenberg, Claudia, Wareham, Nicholas J.
Publicado no Diabetes Care (2015)

Next-Generation Sequencing and In Vitro Expression Study of ADAMTS13 Single Nucleotide Variants in Deep Vein Thrombosis

Por Pagliari, Maria Teresa, Lotta, Luca A., de Haan, Hugoline G., Valsecchi, Carla, Casoli, Gloria, Pontiggia, Silvia, Martinelli, Ida, Passamonti, Serena M., Rosendaal, Frits R., Peyvandi, Flora
Publicado no PLoS One (2016)

A Systematic Review of Biomarkers and Risk of Incident Type 2 Diabetes: An Overview of Epidemiological, Prediction and Aetiological Research Literature

Por Abbasi, Ali, Sahlqvist, Anna-Stina, Lotta, Luca, Brosnan, Julia M., Vollenweider, Peter, Giabbanelli, Philippe, Nunez, Derek J., Waterworth, Dawn, Scott, Robert A., Langenberg, Claudia, Wareham, Nicholas J.
Publicado no PLoS One (2016)

Preoperative Hematocrit Concentration and the Risk of Stroke in Patients Undergoing Isolated Coronary-Artery Bypass Grafting

Por Musallam, Khaled M., Jamali, Faek R., Rosendaal, Frits R., Richards, Toby, Spahn, Donat R., Khavandi, Kaivan, Barakat, Iskandar, Demoss, Benjamin, Lotta, Luca A., Peyvandi, Flora, Sfeir, Pier M.
Publicado em 2013

Residual plasmatic activity of ADAMTS13 is correlated with phenotype severity in congenital thrombotic thrombocytopenic purpura

Por Lotta, Luca A., Wu, Haifeng M., Mackie, Ian J., Noris, Marina, Veyradier, Agnes, Scully, Marie A., Remuzzi, Giuseppe, Coppo, Paul, Liesner, Ri, Donadelli, Roberta, Loirat, Chantal, Gibbs, Richard A., Horne, April, Yang, Shangbin, Garagiola, Isabella, Musallam, Khaled M., Peyvandi, Flora
Publicado em 2012

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

Por Lotta, Luca A, Wang, Mark, Yu, Jin, Martinelli, Ida, Yu, Fuli, Passamonti, Serena M, Consonni, Dario, Pappalardo, Emanuela, Menegatti, Marzia, Scherer, Steven E, Lewis, Lora L, Akbar, Humeira, Wu, Yuanqing, Bainbridge, Matthew N, Muzny, Donna M, Mannucci, Pier M, Gibbs, Richard A, Peyvandi, Flora
Publicado em 2012

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Por Østergaard, Søren D., Mukherjee, Shubhabrata, Sharp, Stephen J., Proitsi, Petroula, Lotta, Luca A., Day, Felix, Perry, John R. B., Boehme, Kevin L., Walter, Stefan, Kauwe, John S., Gibbons, Laura E., Larson, Eric B., Powell, John F., Langenberg, Claudia, Crane, Paul K., Wareham, Nicholas J., Scott, Robert A.
Publicado no PLoS Med (2015)

Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis

Por Nead, Kevin T., Sharp, Stephen J., Thompson, Deborah J., Painter, Jodie N., Savage, David B., Semple, Robert K., Barker, Adam, Perry, John R. B., Attia, John, Dunning, Alison M., Easton, Douglas F., Holliday, Elizabeth, Lotta, Luca A., O’Mara, Tracy, McEvoy, Mark, Pharoah, Paul D. P., Scott, Rodney J., Spurdle, Amanda B., Langenberg, Claudia, Wareham, Nicholas J., Scott, Robert A.
Publicado no J Natl Cancer Inst (2015)

Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

Por Yaghootkar, Hanieh, Lotta, Luca A., Tyrrell, Jessica, Smit, Roelof A. J., Jones, Sam E., Donnelly, Louise, Beaumont, Robin, Campbell, Archie, Tuke, Marcus A., Hayward, Caroline, Ruth, Katherine S., Padmanabhan, Sandosh, Jukema, J. Wouter, Palmer, Colin C., Hattersley, Andrew, Freathy, Rachel M., Langenberg, Claudia, Wareham, Nicholas J., Wood, Andrew R., Murray, Anna, Weedon, Michael N., Sattar, Naveed, Pearson, Ewan, Scott, Robert A., Frayling, Timothy M.
Publicado no Diabetes (2016)

Hypoinsulinaemic, hypoketotic hypoglycaemia due to mosaic genetic activation of PI3-kinase

Por Leiter, Sarah M, Parker, Victoria E R, Welters, Alena, Knox, Rachel, Rocha, Nuno, Clark, Graeme, Payne, Felicity, Lotta, Luca, Harris, Julie, Guerrero-Fernández, Julio, González-Casado, Isabel, García-Miñaur, Sixto, Gordo, Gema, Wareham, Nick, Martínez-Glez, Víctor, Allison, Michael, O’Rahilly, Stephen, Barroso, Inês, Meissner, Thomas, Davies, Susan, Hussain, Khalid, Temple, Karen, Barreda-Bonis, Ana-Coral, Kummer, Sebastian, Semple, Robert K
Publicado no Eur J Endocrinol (2017)

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

Por Lotta, Luca A., Scott, Robert A., Sharp, Stephen J., Burgess, Stephen, Luan, Jian’an, Tillin, Therese, Schmidt, Amand F., Imamura, Fumiaki, Stewart, Isobel D., Perry, John R. B., Marney, Luke, Koulman, Albert, Karoly, Edward D., Forouhi, Nita G., Sjögren, Rasmus J. O., Näslund, Erik, Zierath, Juleen R., Krook, Anna, Savage, David B., Griffin, Julian L., Chaturvedi, Nishi, Hingorani, Aroon D., Khaw, Kay-Tee, Barroso, Inês, McCarthy, Mark I., O’Rahilly, Stephen, Wareham, Nicholas J., Langenberg, Claudia
Publicado no PLoS Med (2016)

Association between LDL-cholesterol lowering genetic variants and risk of type 2 diabetes

Por Lotta, Luca A., Sharp, Stephen. J, Burgess, Stephen, Perry, John R. B., Stewart, Isobel. D, Willems, Sara M., Luan, Jian’an, Ardanaz, Eva, Arriola, Larraitz, Balkau, Beverley, Boeing, Heiner, Deloukas, Panos, Forouhi, Nita G, Franks, Paul W, Grioni, Sara, Kaaks, Rudolf, Key, Timothy J, Navarro, Carmen, Nilsson, Peter M, Overvad, Kim, Palli, Domenico, Panico, Salvatore, Quirós, Jose-Ramón, Riboli, Elio, Rolandsson, Olov, Sacerdote, Carlotta, Salamanca, Elena C, Slimani, Nadia, Spijkerman, Annemieke MW, Tjonneland, Anne, Tumino, Rosario, van der A, Daphne L, van der Schouw, Yvonne T, McCarthy, Mark I., Barroso, Inês, O’Rahilly, Stephen, Savage, David. B, Sattar, Naveed, Langenberg, Claudia, Scott, Robert. A, Wareham, Nicholas J.
Publicado no JAMA (2016)

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity

Por Scott, Robert A, Fall, Tove, Pasko, Dorota, Barker, Adam, Sharp, Stephen J, Arriola, Larraitz, Balkau, Beverley, Barricarte, Aurelio, Barroso, Inês, Boeing, Heiner, Clavel-Chapelon, Françoise, Crowe, Francesca L, Dekker, Jacqueline M, Fagherazzi, Guy, Ferrannini, Ele, Forouhi, Nita G, Franks, Paul W, Gavrila, Diana, Giedraitis, Vilmantas, Grioni, Sara, Groop, Leif C, Kaaks, Rudolf, Key, Timothy J, Kühn, Tilman, Lotta, Luca A, Nilsson, Peter M, Overvad, Kim, Palli, Domenico, Panico, Salvatore, Quirós, J. Ramón, Rolandsson, Olov, Roswall, Nina, Sacerdote, Carlotta, Sala, Núria, Sánchez, María-José, Schulze, Matthias B, Siddiq, Afshan, Slimani, Nadia, Sluijs, Ivonne, Spijkerman, Annemieke MW, Tjonneland, Anne, Tumino, Rosario, van der A, Daphne L, Yaghootkar, Hanieh, McCarthy, Mark I, Semple, Robert K, Riboli, Elio, Walker, Mark, Ingelsson, Erik, Frayling, Tim M, Savage, David B, Langenberg, Claudia, Wareham, Nicholas J
Publicado no Diabetes (2014)

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

Por Willems, Sara M., Wright, Daniel J., Day, Felix R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay, Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Miyamoto-Mikami, Eri, Rivas, Manuel A., White, Tom, Loh, Po-Ru, Aadahl, Mette, Amin, Najaf, Attia, John R., Austin, Krista, Benyamin, Beben, Brage, Søren, Cheng, Yu-Ching, Cięszczyk, Paweł, Derave, Wim, Eriksson, Karl-Fredrik, Eynon, Nir, Linneberg, Allan, Lucia, Alejandro, Massidda, Myosotis, Mitchell, Braxton D., Miyachi, Motohiko, Murakami, Haruka, Padmanabhan, Sandosh, Pandey, Ashutosh, Papadimitriou, Ioannis, Rajpal, Deepak K., Sale, Craig, Schnurr, Theresia M., Sessa, Francesco, Shrine, Nick, Tobin, Martin D., Varley, Ian, Wain, Louise V., Wray, Naomi R., Lindgren, Cecilia M., MacArthur, Daniel G., Waterworth, Dawn M., McCarthy, Mark I., Pedersen, Oluf, Khaw, Kay-Tee, Kiel, Douglas P., Pitsiladis, Yannis, Fuku, Noriyuki, Franks, Paul W., North, Kathryn N., van Duijn, Cornelia M., Mather, Karen A., Hansen, Torben, Hansson, Ola, Spector, Tim, Murabito, Joanne M., Richards, J. Brent, Rivadeneira, Fernando, Langenberg, Claudia, Perry, John R. B., Wareham, Nick J., Scott, Robert A.
Publicado no Nat Commun (2017)