Residual plasmatic activity of ADAMTS13 is correlated with phenotype severity in congenital thrombotic thrombocytopenic purpura

The quantification of residual plasmatic ADAMTS13 activity in congenital thrombotic thrombocytopenic purpura (TTP) patients is constrained by limitations in sensitivity and reproducibility of commonly used assays at low levels of ADAMTS13 activity, blunting efforts to establish genotype-phenotype co...

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Hlavní autoři: Lotta, Luca A., Wu, Haifeng M., Mackie, Ian J., Noris, Marina, Veyradier, Agnes, Scully, Marie A., Remuzzi, Giuseppe, Coppo, Paul, Liesner, Ri, Donadelli, Roberta, Loirat, Chantal, Gibbs, Richard A., Horne, April, Yang, Shangbin, Garagiola, Isabella, Musallam, Khaled M., Peyvandi, Flora
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721603/
https://ncbi.nlm.nih.gov/pubmed/22529288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-403113
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