Residual plasmatic activity of ADAMTS13 is correlated with phenotype severity in congenital thrombotic thrombocytopenic purpura

The quantification of residual plasmatic ADAMTS13 activity in congenital thrombotic thrombocytopenic purpura (TTP) patients is constrained by limitations in sensitivity and reproducibility of commonly used assays at low levels of ADAMTS13 activity, blunting efforts to establish genotype-phenotype co...

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Autors principals: Lotta, Luca A., Wu, Haifeng M., Mackie, Ian J., Noris, Marina, Veyradier, Agnes, Scully, Marie A., Remuzzi, Giuseppe, Coppo, Paul, Liesner, Ri, Donadelli, Roberta, Loirat, Chantal, Gibbs, Richard A., Horne, April, Yang, Shangbin, Garagiola, Isabella, Musallam, Khaled M., Peyvandi, Flora
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721603/
https://ncbi.nlm.nih.gov/pubmed/22529288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-403113
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