ADAMTS13 Secretion and Residual Activity among Patients with Congenital Thrombotic Thrombocytopenic Purpura with and without Renal Impairment

BACKGROUND AND OBJECTIVES: Acute renal impairment is observed in 11%–23% of patients with congenital thrombotic thrombocytopenic purpura (TTP) and deficiency of a disintegrin and metalloprotease with thrombospondin motifs 13 (ADAMTS13, a metalloprotease that cleaves von Willebrand factor [VWF] multi...

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Bibliografiske detaljer
Udgivet i:Clin J Am Soc Nephrol
Main Authors: Rurali, Erica, Banterla, Federica, Donadelli, Roberta, Bresin, Elena, Galbusera, Miriam, Gastoldi, Sara, Peyvandi, Flora, Underwood, Mary, Remuzzi, Giuseppe, Noris, Marina
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2015
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633781/
https://ncbi.nlm.nih.gov/pubmed/26342041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.01700215
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