Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis

Rare mutations in PROC, PROS1 or SERPINC1 as well as common variants in F5, F2, F11 and SERPINC1 have been identified as risk factors for deep vein thrombosis (DVT). To identify novel genetic risk factors for DVT, we have developed and applied next-generation DNA sequencing (NGS) of the coding area...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gorski, Marcin M., Lotta, Luca A., Pappalardo, Emanuela, de Haan, Hugoline G., Passamonti, Serena M., van Hylckama Vlieg, Astrid, Martinelli, Ida, Peyvandi, Flora
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794167/
https://ncbi.nlm.nih.gov/pubmed/26982741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151347
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