Biology-driven cancer drug development: back to the future

nork Lord, Christopher J, Ashworth, Alan
Argitaratua 2010

PARP Inhibitors: The First Synthetic Lethal Targeted Therapy

nork Lord, Christopher J., Ashworth, Alan
Argitaratua izan da Science (2017)

Nuclear envelope–vacuole contacts mitigate nuclear pore complex assembly stress

nork Lord, Christopher L., Wente, Susan R.
Argitaratua izan da J Cell Biol (2020)

The Highly Conserved COPII Coat Complex Sorts Cargo from the Endoplasmic Reticulum and Targets It to the Golgi

nork Lord, Christopher, Ferro-Novick, Susan, Miller, Elizabeth A.
Argitaratua 2013

Nup100 regulates Saccharomyces cerevisiae replicative life span by mediating the nuclear export of specific tRNAs

nork Lord, Christopher L., Ospovat, Ophir, Wente, Susan R.
Argitaratua izan da RNA (2017)

Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions

nork Lord, Christopher J, Quinn, Niall, Ryan, Colm J
Argitaratua izan da eLife (2020)

NLK Is a Novel Therapeutic Target for PTEN Deficient Tumour Cells

nork Mendes-Pereira, Ana M., Lord, Christopher J., Ashworth, Alan
Argitaratua 2012

Driver oncogenes but not as we know them - targetable fusion genes in breast cancer

nork Natrajan, Rachael, Tutt, Andrew N. J., Lord, Christopher J.
Argitaratua izan da Cancer Discov (2018)

CancerGD: A Resource for Identifying and Interpreting Genetic Dependencies in Cancer

nork Bridgett, Stephen, Campbell, James, Lord, Christopher J., Ryan, Colm J.
Argitaratua izan da Cell Syst (2017)

An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence

nork Rovillain, Emilie, Mansfield, Louise, Lord, Christopher J, Ashworth, Alan, Jat, Parmjit S
Argitaratua 2011

Directing the use of DDR kinase inhibitors in cancer treatment

nork Brandsma, Inger, Fleuren, Emmy D.G., Williamson, Chris T., Lord, Christopher J.
Argitaratua izan da Expert Opin Investig Drugs (2017)

A Machine-Learning Tool Concurrently Models Single Omics and Phenome Data for Functional Subtyping and Personalized Cancer Medicine

nork Nyamundanda, Gift, Eason, Katherine, Guinney, Justin, Lord, Christopher J., Sadanandam, Anguraj
Argitaratua izan da Cancers (Basel) (2020)

Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae

nork Lord, Christopher L., Timney, Benjamin L., Rout, Michael P., Wente, Susan R.
Argitaratua izan da J Cell Biol (2015)

A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events

nork Ryan, Colm J., Kennedy, Susan, Bajrami, Ilirjana, Matallanas, David, Lord, Christopher J.
Argitaratua izan da Cell Syst (2017)

Beyond DNA repair: the novel immunological potential of PARP inhibitors

nork Chabanon, Roman M., Soria, Jean-Charles, Lord, Christopher J., Postel-Vinay, Sophie
Argitaratua izan da Mol Cell Oncol (2019)

DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells

nork Gudmundsdottir, Katrin, Lord, Christopher J, Witt, Emily, Tutt, Andrew N J, Ashworth, Alan
Argitaratua 2004

Structural basis for recruitment of BRCA2 by PALB2

nork Oliver, Antony W, Swift, Sally, Lord, Christopher J, Ashworth, Alan, Pearl, Laurence H
Argitaratua 2009

Structural basis for recruitment of BRCA2 by PALB2

nork Oliver, Antony W, Swift, Sally, Lord, Christopher J, Ashworth, Alan, Pearl, Laurence H
Argitaratua izan da EMBO Rep (2017)

Ultrasound-guided muscle biopsy: a practical alternative for investigation of myopathy

nork Raithatha, Anish, Ashraghi, Mohammad Reza, Lord, Christopher, Limback-Stanic, Clara, Viegas, Stuart, Amiras, Dimitri
Argitaratua izan da Skeletal Radiol (2020)

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity

nork Frankum, Jessica, Moudry, Pavel, Brough, Rachel, Hodny, Zdenek, Ashworth, Alan, Bartek, Jiri, Lord, Christopher J.
Argitaratua izan da Oncotarget (2015)