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Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae
The eukaryotic nuclear permeability barrier and selective nucleocytoplasmic transport are maintained by nuclear pore complexes (NPCs), large structures composed of ∼30 proteins (nucleoporins [Nups]). NPC structure and function are disrupted in aged nondividing metazoan cells, although it is unclear...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362458/ https://ncbi.nlm.nih.gov/pubmed/25778920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412024 |
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