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Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae
The eukaryotic nuclear permeability barrier and selective nucleocytoplasmic transport are maintained by nuclear pore complexes (NPCs), large structures composed of ∼30 proteins (nucleoporins [Nups]). NPC structure and function are disrupted in aged nondividing metazoan cells, although it is unclear...
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| Pubblicato in: | J Cell Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362458/ https://ncbi.nlm.nih.gov/pubmed/25778920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412024 |
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