Simple rules for passive diffusion through the nuclear pore complex

Passive macromolecular diffusion through nuclear pore complexes (NPCs) is thought to decrease dramatically beyond a 30–60-kD size threshold. Using thousands of independent time-resolved fluorescence microscopy measurements in vivo, we show that the NPC lacks such a firm size threshold; instead, it f...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Timney, Benjamin L., Raveh, Barak, Mironska, Roxana, Trivedi, Jill M., Kim, Seung Joong, Russel, Daniel, Wente, Susan R., Sali, Andrej, Rout, Michael P.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2016
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057280/
https://ncbi.nlm.nih.gov/pubmed/27697925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201601004
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