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Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex

Nucleocytoplasmic transport is mediated by the interaction of transport factors (TFs) with disordered phenylalanine-glycine (FG) repeats that fill the central channel of the nuclear pore complex (NPC). However, the mechanism by which TFs rapidly diffuse through multiple FG repeats without compromisi...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Raveh, Barak, Karp, Jerome M., Sparks, Samuel, Dutta, Kaushik, Rout, Michael P., Sali, Andrej, Cowburn, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983827/
https://ncbi.nlm.nih.gov/pubmed/27091992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522663113
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