Structural basis for recruitment of BRCA2 by PALB2

The breast cancer 2, early onset protein (BRCA2) is central to the repair of DNA damage by homologous recombination. BRCA2 recruits the recombinase RAD51 to sites of damage, regulates its assembly into nucleoprotein filaments and thereby promotes homologous recombination. Localization of BRCA2 to nu...

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Bibliografske podrobnosti
Main Authors: Oliver, Antony W, Swift, Sally, Lord, Christopher J, Ashworth, Alan, Pearl, Laurence H
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
Teme:
Scientific Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750052/
https://ncbi.nlm.nih.gov/pubmed/19609323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.126
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