Structural basis for recruitment of BRCA2 by PALB2

The breast cancer 2, early onset protein (BRCA2) is central to the repair of DNA damage by homologous recombination. BRCA2 recruits the recombinase RAD51 to sites of damage, regulates its assembly into nucleoprotein filaments and thereby promotes homologous recombination. Localization of BRCA2 to nu...

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Detalles Bibliográficos
Autores principales: Oliver, Antony W, Swift, Sally, Lord, Christopher J, Ashworth, Alan, Pearl, Laurence H
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2009
Materias:
Scientific Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750052/
https://ncbi.nlm.nih.gov/pubmed/19609323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.126
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