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The structural basis for substrate recognition by mammalian polynucleotide kinase 3’ phosphatase
Mammalian polynucleotide kinase 3’ phosphatase (PNK) plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base-excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extensi...
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| 發表在: | Mol Cell |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820033/ https://ncbi.nlm.nih.gov/pubmed/22055185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.036 |
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