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Structure-function Analysis of the 3′ Phosphatase Component of T4 Polynucleotide Kinase/Phosphatase

T4 polynucleotide kinase/phosphatase (Pnkp) exemplifies a family of bifunctional enzymes with 5′-kinase and 3′-phosphatase activities that function in nucleic acid repair. T4 Pnkp is a homotetramer of a 301-aa polypeptide, which consists of an N-terminal kinase domain of the P-loop phosphotransferas...

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Bibliografiske detaljer
Main Authors: Zhu, Hui, Smith, Paul, Wang, Li Kai, Shuman, Stewart
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761019/
https://ncbi.nlm.nih.gov/pubmed/17493655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.03.059
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