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Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system
Pnkp is the end-healing and end-sealing component of an RNA repair system present in diverse bacteria from many phyla. Pnkp is composed of three catalytic modules: an N-terminal polynucleotide 5′-kinase, a central 2′,3′ phosphatase, and a C-terminal ligase. Here we report the crystal structure of th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504678/ https://ncbi.nlm.nih.gov/pubmed/23118415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036061.112 |
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