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Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system

Pnkp is the end-healing and end-sealing component of an RNA repair system present in diverse bacteria from many phyla. Pnkp is composed of three catalytic modules: an N-terminal polynucleotide 5′-kinase, a central 2′,3′ phosphatase, and a C-terminal ligase. Here we report the crystal structure of th...

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Bibliografski detalji
Glavni autori: Wang, Li Kai, Das, Ushati, Smith, Paul, Shuman, Stewart
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504678/
https://ncbi.nlm.nih.gov/pubmed/23118415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036061.112
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