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Mechanism of RNA 2′,3′-cyclic phosphate end healing by T4 polynucleotide kinase–phosphatase

T4 polynucleotide kinase–phosphatase (Pnkp) exemplifies a family of enzymes with 5′-kinase and 3′-phosphatase activities that function in nucleic acid repair. The polynucleotide 3′-phosphatase reaction is executed by the Pnkp C-terminal domain, which belongs to the DxDxT acylphosphatase superfamily....

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Bibliografiska uppgifter
Huvudupphovsmän: Das, Ushati, Shuman, Stewart
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592404/
https://ncbi.nlm.nih.gov/pubmed/23118482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks977
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