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Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial Pnkp•Hen1 RNA repair system
Clostridium thermocellum Pnkp is the end-healing and end-sealing subunit of a bacterial RNA repair system. CthPnkp is composed of three catalytic modules: an N-terminal 5′-OH polynucleotide kinase; a central 2′,3′ phosphatase; and a C-terminal ligase. The crystal structure of the kinase domain bound...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855621/ https://ncbi.nlm.nih.gov/pubmed/23721485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400412x |
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