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DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells

BRCA2 is a breast cancer susceptibility gene implicated in the repair of double-strand breaks by homologous recombination with RAD51. BRCA2 associates with a 70-amino-acid protein, DSS1, but the functional significance of this interaction has remained unclear. Recently, deficiency of a DSS1 ortholog...

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Bibliografske podrobnosti
Main Authors: Gudmundsdottir, Katrin, Lord, Christopher J, Witt, Emily, Tutt, Andrew N J, Ashworth, Alan
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299155/
https://ncbi.nlm.nih.gov/pubmed/15359272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400255
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