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Mutations in yeast Rad51 that partially bypass the requirement for Rad55 and Rad57 in DNA repair by increasing the stability of Rad51–DNA complexes

Yeast Rad51 promotes homologous pairing and strand exchange in vitro, but this activity is inefficient in the absence of the accessory proteins, RPA, Rad52, Rad54 and the Rad55–Rad57 heterodimer. A class of rad51 alleles was isolated that suppresses the requirement for RAD55 and RAD57 in DNA repair,...

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Detalhes bibliográficos
Main Authors: Fortin, Gary S., Symington, Lorraine S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126052/
https://ncbi.nlm.nih.gov/pubmed/12065428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf293
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