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p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene
DNA repair by homologous recombination is involved in maintaining genome stability. Previous data report that wild-type p53 suppresses homologous recombination and physically interacts with Rad51. Here, we show the in vivo binding of wild-type p53 to a p53 response element in the promoter of Rad51 a...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369244/ https://ncbi.nlm.nih.gov/pubmed/16322760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400587 |
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