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An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence
BACKGROUND: Cellular senescence is an irreversible cell cycle arrest that normal cells undergo in response to progressive shortening of telomeres, changes in telomeric structure, oncogene activation or oxidative stress and acts as an important tumour suppressor mechanism. RESULTS: To identify the do...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161017/ https://ncbi.nlm.nih.gov/pubmed/21740549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-355 |
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