Biology-driven cancer drug development: back to the future

af Lord, Christopher J, Ashworth, Alan
Udgivet 2010

PARP Inhibitors: The First Synthetic Lethal Targeted Therapy

af Lord, Christopher J., Ashworth, Alan
Udgivet i Science (2017)

Nuclear envelope–vacuole contacts mitigate nuclear pore complex assembly stress

af Lord, Christopher L., Wente, Susan R.
Udgivet i J Cell Biol (2020)

The Highly Conserved COPII Coat Complex Sorts Cargo from the Endoplasmic Reticulum and Targets It to the Golgi

af Lord, Christopher, Ferro-Novick, Susan, Miller, Elizabeth A.
Udgivet 2013

Nup100 regulates Saccharomyces cerevisiae replicative life span by mediating the nuclear export of specific tRNAs

af Lord, Christopher L., Ospovat, Ophir, Wente, Susan R.
Udgivet i RNA (2017)

Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions

af Lord, Christopher J, Quinn, Niall, Ryan, Colm J
Udgivet i eLife (2020)

NLK Is a Novel Therapeutic Target for PTEN Deficient Tumour Cells

af Mendes-Pereira, Ana M., Lord, Christopher J., Ashworth, Alan
Udgivet 2012

Driver oncogenes but not as we know them - targetable fusion genes in breast cancer

af Natrajan, Rachael, Tutt, Andrew N. J., Lord, Christopher J.
Udgivet i Cancer Discov (2018)

CancerGD: A Resource for Identifying and Interpreting Genetic Dependencies in Cancer

af Bridgett, Stephen, Campbell, James, Lord, Christopher J., Ryan, Colm J.
Udgivet i Cell Syst (2017)

An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence

af Rovillain, Emilie, Mansfield, Louise, Lord, Christopher J, Ashworth, Alan, Jat, Parmjit S
Udgivet 2011

Directing the use of DDR kinase inhibitors in cancer treatment

af Brandsma, Inger, Fleuren, Emmy D.G., Williamson, Chris T., Lord, Christopher J.
Udgivet i Expert Opin Investig Drugs (2017)

A Machine-Learning Tool Concurrently Models Single Omics and Phenome Data for Functional Subtyping and Personalized Cancer Medicine

af Nyamundanda, Gift, Eason, Katherine, Guinney, Justin, Lord, Christopher J., Sadanandam, Anguraj
Udgivet i Cancers (Basel) (2020)

Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae

af Lord, Christopher L., Timney, Benjamin L., Rout, Michael P., Wente, Susan R.
Udgivet i J Cell Biol (2015)

A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events

af Ryan, Colm J., Kennedy, Susan, Bajrami, Ilirjana, Matallanas, David, Lord, Christopher J.
Udgivet i Cell Syst (2017)

Beyond DNA repair: the novel immunological potential of PARP inhibitors

af Chabanon, Roman M., Soria, Jean-Charles, Lord, Christopher J., Postel-Vinay, Sophie
Udgivet i Mol Cell Oncol (2019)

DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells

af Gudmundsdottir, Katrin, Lord, Christopher J, Witt, Emily, Tutt, Andrew N J, Ashworth, Alan
Udgivet 2004

Structural basis for recruitment of BRCA2 by PALB2

af Oliver, Antony W, Swift, Sally, Lord, Christopher J, Ashworth, Alan, Pearl, Laurence H
Udgivet 2009

Structural basis for recruitment of BRCA2 by PALB2

af Oliver, Antony W, Swift, Sally, Lord, Christopher J, Ashworth, Alan, Pearl, Laurence H
Udgivet i EMBO Rep (2017)

Ultrasound-guided muscle biopsy: a practical alternative for investigation of myopathy

af Raithatha, Anish, Ashraghi, Mohammad Reza, Lord, Christopher, Limback-Stanic, Clara, Viegas, Stuart, Amiras, Dimitri
Udgivet i Skeletal Radiol (2020)

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity

af Frankum, Jessica, Moudry, Pavel, Brough, Rachel, Hodny, Zdenek, Ashworth, Alan, Bartek, Jiri, Lord, Christopher J.
Udgivet i Oncotarget (2015)