Structure and mechanism of ATP-binding cassette transporters

Tekijä Locher, Kaspar P.
Julkaistu 2008

Structure of the human transcobalamin beta domain in four distinct states

Tekijä Bloch, Joël S., Ruetz, Markus, Kräutler, Bernhard, Locher, Kaspar P.
Julkaisussa PLoS One (2017)

A distinct mechanism for the ABC transporter BtuCD-F revealed by the dynamics of complex formation

Tekijä Lewinson, Oded, Lee, Allen T., Locher, Kaspar P., Rees, Douglas C.
Julkaistu 2010

The structure of Escherichia coli BtuF and binding to its cognate ATP binding cassette transporter

Tekijä Borths, Elizabeth L., Locher, Kaspar P., Lee, Allen T., Rees, Douglas C.
Julkaistu 2002

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Tekijä Alam, Amer, Kowal, Julia, Broude, Eugenia, Roninson, Igor, Locher, Kaspar P.
Julkaisussa Science (2019)

Transmembrane Gate Movements in the Type II ATP-binding Cassette (ABC) Importer BtuCD-F during Nucleotide Cycle

Tekijä Joseph, Benesh, Jeschke, Gunnar, Goetz, Birke A., Locher, Kaspar P., Bordignon, Enrica
Julkaistu 2011

Structure of bacterial oligosaccharyltransferase PglB bound to a reactive LLO and an inhibitory peptide

Tekijä Napiórkowska, Maja, Boilevin, Jérémy, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P.
Julkaisussa Sci Rep (2018)

In Vitro Folding and Assembly of the Escherichia coli ATP-binding Cassette Transporter, BtuCD

Tekijä Di Bartolo, Natalie D., Hvorup, Rikki N., Locher, Kaspar P., Booth, Paula J.
Julkaistu 2011

Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody

Tekijä Perez, Camilo, Köhler, Martin, Janser, Daniel, Pardon, Els, Steyaert, Jan, Zenobi, Renato, Locher, Kaspar P.
Julkaisussa Sci Rep (2017)

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Tekijä Manolaridis, Ioannis, Jackson, Scott M., Taylor, Nicholas M. I., Kowal, Julia, Stahlberg, Henning, Locher, Kaspar P.
Julkaisussa Nature (2018)

Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1

Tekijä Nosol, Kamil, Romane, Ksenija, Irobalieva, Rossitza N., Alam, Amer, Kowal, Julia, Fujita, Naoya, Locher, Kaspar P.
Julkaisussa Proc Natl Acad Sci U S A (2020)

Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism

Tekijä Yu, Qin, Ni, Dongchun, Kowal, Julia, Manolaridis, Ioannis, Jackson, Scott M., Stahlberg, Henning, Locher, Kaspar P.
Julkaisussa Nat Commun (2021)

Structural basis of the molecular ruler mechanism of a bacterial glycosyltransferase

Tekijä Ramírez, Ana S., Boilevin, Jérémy, Mehdipour, Ahmad Reza, Hummer, Gerhard, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P.
Julkaisussa Nat Commun (2018)

Mechanism of Bacterial Oligosaccharyltransferase: IN VITRO QUANTIFICATION OF SEQUON BINDING AND CATALYSIS

Tekijä Gerber, Sabina, Lizak, Christian, Michaud, Gaëlle, Bucher, Monika, Darbre, Tamis, Aebi, Markus, Reymond, Jean-Louis, Locher, Kaspar P.
Julkaistu 2013

Structural basis of transcobalamin recognition by human CD320 receptor

Tekijä Alam, Amer, Woo, Jae-Sung, Schmitz, Jennifer, Prinz, Bernadette, Root, Katharina, Chen, Fan, Bloch, Joël S., Zenobi, Renato, Locher, Kaspar P.
Julkaisussa Nat Commun (2016)

Characterization of the single-subunit oligosaccharyltransferase STT3A from Trypanosoma brucei using synthetic peptides and lipid-linked oligosaccharide analogs

Tekijä Ramírez, Ana S, Boilevin, Jérémy, Biswas, Rasomoy, Gan, Bee Ha, Janser, Daniel, Aebi, Markus, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P
Julkaisussa Glycobiology (2017)

Chemo-enzymatic synthesis of lipid-linked GlcNAc(2)Man(5) oligosaccharides using recombinant Alg1, Alg2 and Alg11 proteins

Tekijä Ramírez, Ana S, Boilevin, Jérémy, Lin, Chia-Wei, Ha Gan, Bee, Janser, Daniel, Aebi, Markus, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P
Julkaisussa Glycobiology (2017)

Substrate specificities and reaction kinetics of the yeast oligosaccharyltransferase isoforms

Tekijä Eyring, Jillianne, Lin, Chia-Wei, Ngwa, Elsy Mankah, Boilevin, Jérémy, Pesciullesi, Giorgio, Locher, Kaspar P., Darbre, Tamis, Reymond, Jean-Louis, Aebi, Markus
Julkaisussa J Biol Chem (2021)

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1

Tekijä Alam, Amer, Küng, Raphael, Kowal, Julia, McLeod, Robert A., Tremp, Nina, Broude, Eugenia V., Roninson, Igor B., Stahlberg, Henning, Locher, Kaspar P.
Julkaisussa Proc Natl Acad Sci U S A (2018)

A Catalytically Essential Motif in External Loop 5 of the Bacterial Oligosaccharyltransferase PglB

Tekijä Lizak, Christian, Gerber, Sabina, Zinne, Daria, Michaud, Gaëlle, Schubert, Mario, Chen, Fan, Bucher, Monika, Darbre, Tamis, Zenobi, Renato, Reymond, Jean-Louis, Locher, Kaspar P.
Julkaistu 2014