Characterization of the single-subunit oligosaccharyltransferase STT3A from Trypanosoma brucei using synthetic peptides and lipid-linked oligosaccharide analogs

The initial transfer of a complex glycan in protein N-glycosylation is catalyzed by oligosaccharyltransferase (OST), which is generally a multisubunit membrane protein complex in the endoplasmic reticulum but a single-subunit enzyme (ssOST) in some protists. To investigate the reaction mechanism of...

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Bibliographic Details
Published in:Glycobiology
Main Authors: Ramírez, Ana S, Boilevin, Jérémy, Biswas, Rasomoy, Gan, Bee Ha, Janser, Daniel, Aebi, Markus, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Original articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421464/
https://ncbi.nlm.nih.gov/pubmed/28204532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx017
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