Chemo-enzymatic synthesis of lipid-linked GlcNAc(2)Man(5) oligosaccharides using recombinant Alg1, Alg2 and Alg11 proteins

The biosynthesis of eukaryotic lipid-linked oligosaccharides (LLOs) that act as donor substrates in eukaryotic protein N-glycosylation starts on the cytoplasmic side of the endoplasmic reticulum and includes the sequential addition of five mannose units to dolichol-pyrophosphate-GlcNAc(2). These rea...

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Publicado en:Glycobiology
Main Authors: Ramírez, Ana S, Boilevin, Jérémy, Lin, Chia-Wei, Ha Gan, Bee, Janser, Daniel, Aebi, Markus, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Original articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881667/
https://ncbi.nlm.nih.gov/pubmed/28575298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx045
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